Cardiovascular prevention

One daily pill. One care team. A simpler path to a healthier heart.

Poly-Pill is a physician-supervised program for adults with high blood pressure and high cholesterol. It combines proven medicine classes in a single daily pill, adds home blood pressure monitoring, and keeps your own doctor in the loop.

What members receive

  • ✓One prescription pill a day in place of several
  • ✓A connected home blood pressure monitor
  • ✓A licensed clinical team that reviews readings and adjusts treatment
  • ✓Regular progress reports shared with your primary care doctor
  • ✓Home delivery of refills

The gap we are built to close

Heart attack and stroke are largely driven by two conditions that are common, treatable, and often left uncontrolled. Multiple prescriptions, missed refills, and infrequent check-ins make control hard to reach.

~1 in 2

U.S. adults have high blood pressure.

~1 in 4

U.S. adults with high blood pressure have it under control.

1 pill

Poly-Pill combines blood pressure and cholesterol treatment into a single daily dose.

Source: Centers for Disease Control and Prevention, High Blood Pressure Facts.

How it works

A straightforward program designed around the patient, the prescribing clinician, and the patient's own primary care doctor.

Referral or enrollment

Patients are referred by their primary care practice or health plan, or enroll directly where available.

Clinical review

A licensed clinician reviews history, medications, and labs, and decides whether Poly-Pill is appropriate.

One daily pill

If prescribed, a single daily pill combining a cholesterol-lowering statin with blood pressure medicines is delivered to the home.

Monitor and adjust

Home blood pressure readings are reviewed by the care team, the dose is adjusted as needed, and progress is shared with the primary care doctor.

Built for everyone in the care relationship

Poly-Pill is designed to work alongside existing care, not around it.

Patients

Fewer pills, more support

  • One daily pill in place of a multi-bottle routine
  • A home monitor and a team that watches the numbers
  • Dose changes without waiting for the next office visit
  • Your primary care doctor stays your doctor
Physicians and practices

An extension of your practice

  • Between-visit monitoring and titration support for your patients
  • Regular reports on blood pressure and treatment status
  • Coordination that keeps you informed and in control of the relationship
  • A partner program for practices in value-based arrangements
Health plans and partners

A targeted prevention program

  • Focused on members with high blood pressure and high cholesterol
  • Designed for value-based and risk-bearing arrangements
  • Measurement of blood pressure control and adherence
  • Collaboration with network primary care practices

Grounded in clinical research

The polypill strategy, combining cardiovascular medicine classes in a single daily pill, has been studied in large randomized trials published in leading medical journals.

TIPS-3

Studied a polypill in adults without cardiovascular disease who were at intermediate risk.

New England Journal of Medicine, 2021

PolyIran

Studied a polypill in adults aged 50 to 75 in a large community-based trial.

The Lancet, 2019

SECURE

Studied a polypill-based strategy in older adults after a heart attack.

New England Journal of Medicine, 2022

The formulations studied in these trials differ from one another and from the Poly-Pill formulation. These references describe the research behind the polypill approach and are not claims about the outcomes of the Poly-Pill program. Whether Poly-Pill is appropriate for a given patient is determined by a licensed clinician.

Launching in 2027

Get in touch

Poly-Pill is preparing for launch. Patients can join the interest list, and physicians, practices, health plans, and prospective partners can contact us directly.

Please do not send personal health information by email. If you are having a medical emergency, call 911.